منابع مشابه
Take a deep breath: pulmonary research inspires.
The lung is a complex organ with multiple functions; in addition to facilitating gas exchange, it also serves as the first line of defense against inhaled environmental pathogens and toxins. Given these critical roles, disruption of normal cell function or cell-cell interactions can have devastating health consequences. The articles of this Review Series highlight recent progress in understandi...
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Inhalation of insulin is the first alternative route of insulin administration, which has been developed to such a mature status that the first product (Exubera, Pfizer) was made available to the market and subsequently withdrawn as of early 2008. In view of the relatively low bioavailability of inhaled insulin and the intraindividual variability of the metabolic effect induced (which is in the...
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With EMA approval in December 2015, and US FDA approval in October 2015 of an oncolytic herpesvirus for the treatment of nonresectable melanoma, we now have a novel class of anticancer agents to add to our ever-promising arsenal of cancer (immuno-) therapeutics. Talimogen laherparapvec (T-VEC) therapy involves direct, intratumoral injection of a herpes simplex type 1 (HSV-1) virus which has bee...
متن کاملEvery breath we take.
Of all the risk factors for premature death, the air we breathe is one area over which patients and doctors have little control. In cities health professionals care for patients in environments where air pollution can aggravate existing illness, mostly cardiovascular and respiratory disease, and also damage children’s hearts and lungs as they develop. Today we report that more than half of 2200...
متن کاملEvery Breath You Take
Fuel for thought. A better measure of exposure to jet fuel shows that some military personnel may be at increased risk for adverse health effects from breathing noxious fumes. In this issue, Steve Wing, an associate professor of epidemiology in the School of Public Health at the University of North Carolina at Chapel Hill, and colleagues investigate environmental injustice in North Carolina's s...
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ژورنال
عنوان ژورنال: Immunity
سال: 2016
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2016.06.005